ABSTRACT
The year 2020 was marked by the worldwide COVID-19 pandemic, which caused over 2.5 million deaths by the end of February 2021. Different methods have been established since the beginning to identify infected patients and restrict the spread of the virus. In addition to laboratory analysis, used as the gold standard, several applications have been developed to apply deep learning algorithms to chest X-ray (CXR) images to diagnose patients affected by COVID-19. The literature shows that convolutional neural networks (CNNs) perform well on a single image dataset, but fail to generalize to other sources of data. To overcome this limitation, we present a late fusion approach in which multiple CNNs collaborate to diagnose the CXR scan of a patient, improving the generalizability. Experiments on three datasets publicly available show that the ensemble of CNNs outperforms stand-alone networks, achieving promising performance not only in cross-validation, but also when external validation is used, with an average accuracy of 95.18%. © 2021 IEEE.